MHCII/B2m-KO(NMG)

Mfr.No.	NM-NSG-014
Description	All sequences from the upstream of mouse H2-Ab1 gene exon 2 to the upstream of the H2-Ea-ps gene exon 1 were knocked out to obtain H2-Ab1,H2-Aa,H2-Eb1,H2-Eb2,H2-Ea-ps knockout mouse models.Also, B2m gene was knocked out. These MHC class I and II molecule-deficient mice were on the NMG genetic background and also lacked cell surface expression of both class II-A and class II-E MHC proteins and B2m of class I. NCBI ID: 12010 MGI ID: 88127 Ensembl ID: ENSMUSG00000060802 Pubmed: B2M Human Ortholog: B2M
Nomenclature	NOD.Cg-Prkdc^scidIl2rg^em1SmocH2-Ab1^em1SmocH2-Aa^em1SmocH2-Eb1^em1SmocH2-Eb2^em1SmocH2-Ea-ps^em1SmocB2m^em1Smoc
Strain	Repository Live
KI/KO Gene	B2M
Synonyms	y-m11; beta2m; beta2-m

Research Application	Immunodeficient, Immunodeficiency, Immune System, Transplantation Research

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