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Home / Proteins & Peptide

IL-33, Mouse

SKU : BHP18500060

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iXCells Biotechnologies

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Mfr.No.	IX02772, IX02772-1, IX02772-10
Description	IL-33 is a proinflammatory protein that shares structural and functional characteristics with the IL-1 cytokine family. It binds and signals through the IL-1RL1/ST2 receptor activating NF-kappaB and MAP kinases. IL-33 induces production of TH2 cell related cytokines, including IL-4, IL-5 and IL-13, and exerts multiple inflammation related bioactivities.
Reconstitution	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at <= -20 °C. Further dilutions should be made in appropriate buffered solutions.
Formulation	Lyophilized from a 0.2 um filtered solution in PBS, and 1 mM EDTA.
Molecular Weight	Approximately 17.5 kDa protein containing 158 amino acid residues.
Physical Appearance	Sterile Filtered White lyophilized (freeze-dried) powder.
Source	E. coli
Host	Mouse
Usage	This material is for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.
Endotoxin Level	Less than 1 EU/ug of rMuIL-33 as determined by LAL method.
Bioactivity	Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine D10S cells is less than 0.5 ng/ml, corresponding to a specific activity of 2.0 x 106 IU/mg.

Synonyms	Interleukin-33 (IL-33), Mouse;
Sequence	SIQGTSLLTQ SPASLSTYND QSVSFVLENG CYVINVDDSGKDQEQDQVLL?RYYESPCPAS QSGDGVDGKK LMVNMSPIKD TDIWLHANDKDYSVELQRGD?VSPPEQAFFV LHKKSSDFVS FECKNLPGTY IGVKDNQLALVEEKDESCNN IMFKLSKI

Purity	98 % by SDS-PAGE and HPLC analyses.
Storage	This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C. Avoid repeated freeze/thaw cycles.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHP18500060-1	IX02772-1	1mg	$4492		Add to Cart
BHP18500060-2	IX02772-10	10ug	$199		Add to Cart

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