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Home / Proteins & Peptide

IL-33, Mouse

SKU : BHP18500060

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iXCells Biotechnologies

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Mfr.No.	IX02772, IX02772-1, IX02772-10
Reconstitution	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at <= -20 °C. Further dilutions should be made in appropriate buffered solutions.
Description	IL-33 is a proinflammatory protein that shares structural and functional characteristics with the IL-1 cytokine family. It binds and signals through the IL-1RL1/ST2 receptor activating NF-kappaB and MAP kinases. IL-33 induces production of TH2 cell related cytokines, including IL-4, IL-5 and IL-13, and exerts multiple inflammation related bioactivities.
Formulation	Lyophilized from a 0.2 um filtered solution in PBS, and 1 mM EDTA.
Molecular Weight	Approximately 17.5 kDa protein containing 158 amino acid residues.
Physical Appearance	Sterile Filtered White lyophilized (freeze-dried) powder.
Source	E. coli
Host	Mouse
Usage	This material is for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.
Endotoxin Level	Less than 1 EU/ug of rMuIL-33 as determined by LAL method.
Bioactivity	Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine D10S cells is less than 0.5 ng/ml, corresponding to a specific activity of 2.0 x 106 IU/mg.

Synonyms	Interleukin-33 (IL-33), Mouse;
Sequence	SIQGTSLLTQ SPASLSTYND QSVSFVLENG CYVINVDDSGKDQEQDQVLL?RYYESPCPAS QSGDGVDGKK LMVNMSPIKD TDIWLHANDKDYSVELQRGD?VSPPEQAFFV LHKKSSDFVS FECKNLPGTY IGVKDNQLALVEEKDESCNN IMFKLSKI

Purity	98 % by SDS-PAGE and HPLC analyses.
Storage	This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C. Avoid repeated freeze/thaw cycles.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHP18500060-1	IX02772-1	1mg	$4492		Add to Cart
BHP18500060-2	IX02772-10	10ug	$199		Add to Cart

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