Wiskott-Aldrich syndrome protein family member 3; WASP family protein member 3; Protein WAVE-3; Verprolin homology domain-containing protein 3; WASF3
Antigen
WASF3
Categories
Primary Antibodies
Clonality
polyclonal
Description
Downstream effector molecules involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.Suetsugu S., Biochem. Biophys. Res. Commun. 260:296-302(1999).Sossey-Alaoui K., Mamm. Genome 14:314-322(2003).Nagase T., DNA Res. 5:355-364(1998)
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human WASF3.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Downstream effector molecules involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.
Suetsugu S., Biochem. Biophys. Res. Commun. 260:296-302(1999). Sossey-Alaoui K., Mamm. Genome 14:314-322(2003). Nagase T., DNA Res. 5:355-364(1998)
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total WASF3 protein.
Downstream effector molecules involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.
Pathway
Adherens junction Fc gamma R-mediated phagocytosis
Protein Families
SCAR/WAVE family
Tissue Specificity
Expressed in ovary and brain.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.