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Home / Primary Antibodies / IHC Antibodies

UBA7 Antibody

SKU : BHA10559787

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA991105
Alternative Names	D8; UBE2; ubiquitin-activating enzyme E1 homolog; ubiquitin-activating enzyme E1-like; ubiquitin-activating enzyme E1-related protein
Categories	Primary Antibodies
Clonality	polyclonal
Description	Activates ubiquitin by first adenylating with ATP its C-terminal glycine residue and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP. Catalyzes the ISGylation of influenza A virus NS1 protein.Sutisak Kitareewan, PNAS, Mar 2002; 99: 3806. Keun Il Kim, Mol. Cell. Biol., Jan 2006; 26: 472 - 479. Ian Pitha-Rowe, Cancer Res., Nov 2004; 64: 8109 - 8115.
Host	Rabbit
Immunogen	Synthesized peptide derived from C-terminal of Human UBE1L.
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Activates ubiquitin by first adenylating with ATP its C-terminal glycine residue and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP. Catalyzes the ISGylation of influenza A virus NS1 protein. Sutisak Kitareewan, PNAS, Mar 2002; 99: 3806. Keun Il Kim, Mol. Cell. Biol., Jan 2006; 26: 472 - 479. Ian Pitha-Rowe, Cancer Res., Nov 2004; 64: 8109 - 8115.
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total UBE1L protein.

Uniprot	P41226
Database Links	HGNC:12471 OMIM:191325 KEGG:hsa:7318 STRING:9606.ENSP00000333266 UniGene:Hs.16695
Function	Activates ubiquitin by first adenylating with ATP its C-terminal glycine residue and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP. Catalyzes the ISGylation of influenza A virus NS1 protein.
Pathway	Ubiquitin mediated proteolysis
Protein Families	Ubiquitin-activating E1 family
Tissue Specificity	Expressed in a variety of normal and tumor cell types, but is reduced in lung cancer cell lines.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC, WB ; ELISA ; IHC

Dilution

WB	1:500-1:3000
IHC	1:50-1:100

Tested Application

ELISA,WB,IHC;WB:1:500-1:3000,IHC:1:50-1:100

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10559787	CSB-PA991105	100ul	$297		Add to Cart

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