Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.Murphy S.M., Mol. Biol. Cell 12:3340-3352(2001).Dunham I., Nature 402:489-495(1999).Hirosawa M., DNA Res. 8:1-9(2001).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human TUBGCP6.
Involvement In Disease
Microcephaly and chorioretinopathy, autosomal recessive, 1 (MCCRP1)
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
Murphy S.M., Mol. Biol. Cell 12:3340-3352(2001). Dunham I., Nature 402:489-495(1999). Hirosawa M., DNA Res. 8:1-9(2001).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total TUBGCP6 protein.
Subcellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome