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Home / Primary Antibodies / IHC Antibodies

TFDP1 Antibody

SKU : BHA10559721

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA149329
Alternative Names	E2F DIMERIZATION PARTNER 1; TRANSCRIPTION FACTOR DP1; TRANSCRIPTION FACTOR; SEQUENCE-SPECIFIC; DRTF1
Categories	Primary Antibodies
Clonality	polyclonal
Description	Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F1/DP complex appears to mediate both cell proliferation and apoptosis.K Helin, Genes & Dev., Oct 1993; 7: 1850 - 1861.B Shan, Cell Growth Differ., Jun 1996; 7: 689.Hironori Ishida, J. Biol. Chem., Jul 2005; 280: 24642 - 24648.Wing Y. Chang, J. Biol. Chem., Dec 2004; 279: 51343 - 51353.
Host	Rabbit
Immunogen	Synthesized peptide derived from Human DP-1.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F1/DP complex appears to mediate both cell proliferation and apoptosis. K Helin, Genes & Dev., Oct 1993; 7: 1850 - 1861. B Shan, Cell Growth Differ., Jun 1996; 7: 689. Hironori Ishida, J. Biol. Chem., Jul 2005; 280: 24642 - 24648. Wing Y. Chang, J. Biol. Chem., Dec 2004; 279: 51343 - 51353.
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total DP-1 protein.
Subcellular Location	Nucleus, Cytoplasm

Uniprot	Q14186
Database Links	HGNC:11749 OMIM:189902 KEGG:hsa:7027 STRING:9606.ENSP00000364519 UniGene:Hs.79353
Function	Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication
Pathway	TGF-beta signaling pathway Cell cycle
Protein Families	E2F/DP family
Tissue Specificity	Highest levels in muscle. Also expressed in brain, placenta, liver and kidney. Lower levels in lung and pancreas. Not detected in heart.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IHC, IF

Description

ELISA ; WB ; IHC ; IF, WB ; ELISA ; IHC ; IF

Dilution

WB	1:500-1:3000
IHC	1:50-1:100
IF	1:100-1:500

Tested Application

ELISA,WB,IHC,IF;WB:1:500-1:3000,IHC:1:50-1:100,IF:1:100-1:500

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10559721	CSB-PA149329	100ul	$297		Add to Cart

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