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Home / Primary Antibodies / IHC Antibodies

TEP1 Antibody

SKU : BHA10558011

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA941380
Alternative Names	Telomerase-associated protein 1; Telomerase protein 1; p240; p80 telomerase homolog;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Component of the telomerase ribonucleoprotein complex that is essential for the replication of chromosome termini. Also component of the ribonucleoprotein vaults particle, a multi-subunit structure involved in nucleo-cytoplasmic transport. Responsible for the localizing and stabilizing vault RNA (vRNA) association in the vault ribonucleoprotein particle. Binds to TERC By similarity.Harrington L., Science 275:973-977(1997).Harrington L., Genes Dev. 11:3109-3115(1997).Kickhoefer V.A., J. Biol. Chem. 274:32712-32717(1999).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human TEP1.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Component of the telomerase ribonucleoprotein complex that is essential for the replication of chromosome termini. Also component of the ribonucleoprotein vaults particle, a multi-subunit structure involved in nucleo-cytoplasmic transport. Responsible for the localizing and stabilizing vault RNA (vRNA) association in the vault ribonucleoprotein particle. Binds to TERC By similarity. Harrington L., Science 275:973-977(1997). Harrington L., Genes Dev. 11:3109-3115(1997). Kickhoefer V.A., J. Biol. Chem. 274:32712-32717(1999).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total TEP1 protein.
Subcellular Location	Nucleus, Chromosome, telomere

Uniprot	Q99973
Database Links	HGNC:11726 OMIM:601686 KEGG:hsa:7011 STRING:9606.ENSP00000262715 UniGene:Hs.508835
Function	Component of the telomerase ribonucleoprotein complex that is essential for the replication of chromosome termini. Also component of the ribonucleoprotein vaults particle, a multi-subunit structure involved in nucleo-cytoplasmic transport. Responsible for the localizing and stabilizing vault RNA (vRNA) association in the vault ribonucleoprotein particle. Binds to TERC (By similarity).
Tissue Specificity	Ubiquitous.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, IHC

Description

ELISA ; IHC, IHC ; ELISA

Dilution

IHC	1:50-1:100

Tested Application

ELISA,IHC;IHC:1:50-1:100

Datasheet
ELISA Protocol
Immunohistochemistry (IHC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558011	CSB-PA941380	100ul	$297		Add to Cart

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