major synaptic vesicle protein p38; synaptophysin;
Antigen
SYP
Categories
Primary Antibodies
Clonality
polyclonal
Description
Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity By similarity.Tiffany C. Wheeler, J. Biol. Chem., Mar 2002; 277: 10273 - 10282. RE Leube, J. Cell Biol., Dec 1994; 127: 1589. Reinhard Jahn, J. Neurosci., Mar 1999; 19: 1922. PL Cameron, J. Cell Biol., Oct 1991; 115: 151.
Host
Rabbit
Immunogen
Synthesized peptide derived from Human Synaptophysin.
Involvement In Disease
Mental retardation, X-linked 96 (MRX96)
Raised In
Rabbit
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Relevance
Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity By similarity.
Tiffany C. Wheeler, J. Biol. Chem., Mar 2002; 277: 10273 - 10282. RE Leube, J. Cell Biol., Dec 1994; 127: 1589. Reinhard Jahn, J. Neurosci., Mar 1999; 19: 1922. PL Cameron, J. Cell Biol., Oct 1991; 115: 151.
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total Synaptophysin protein.
Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity).
Protein Families
Synaptophysin/synaptobrevin family
Tissue Specificity
Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.