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Home / Primary Antibodies / IHC Antibodies

SUMO2 Antibody

SKU : BHA10559593

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA099258
Alternative Names	SMT3A; Smt3B; SMT3H1; SUMO-3; HSMT3; SMT3B; SUMO3; Smt3A; SMT3H2; IDDM5; SMT3H4; SUMO-4; dJ281H8.4
Categories	Primary Antibodies
Clonality	polyclonal
Description	This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Host	Rabbit
Immunogen	Synthetic peptide corresponding to a region derived from internal residues of Human SMT3 suppressor of mif two 3 homolog 2/3/4 (S. cerevisiae)
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total SUMO2/SUMO3/SUMO4 protein.
Subcellular Location	Nucleus, Nucleus, PML body

Uniprot	P61956
Database Links	HGNC:11125 OMIM:603042 KEGG:hsa:6613 STRING:9606.ENSP00000405965 UniGene:Hs.380973
Function	Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2, CBX4 or ZNF451
Protein Families	Ubiquitin family, SUMO subfamily
Tissue Specificity	Broadly expressed.

Buffer	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Form	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Format	liquid
Purification	Antigen Affinity Purified
Purity	Antigen Affinity Purified
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC, WB ; ELISA ; IHC

Dilution

WB	1:500-1:3000
IHC	1:50-1:100

Tested Application

ELISA,WB,IHC;WB:1:500-1:3000,IHC:1:50-1:100

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10559593	CSB-PA099258	100ul	$297		Add to Cart

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