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Home / Primary Antibodies / IHC Antibodies

STAT5B (Ab-731) Antibody

SKU : BHA10559099

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA100746
Alternative Names	Signal transducer and activator of transcription 5B;
Antigen	STAT5b
Categories	Primary Antibodies
Clonality	polyclonal
Description	Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription.Zsuzsanna S. Nagy, J. Leukoc. Biol., Oct 2002; 72: 819.Stanislaw M. Stepkowski, Blood, Jan 2002; 99: 680 - 689.Salvador Aznar Benitah, Mol. Biol. Cell, Jan 2003; 14: 40.
Host	Rabbit
Immunogen	Synthesized non-phosphopeptide derived from Human STAT5B around the phosphorylation site of serine 731(A-P-S-P-A).
Involvement In Disease	Growth hormone insensitivity with immunodeficiency (GHII)
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription. Zsuzsanna S. Nagy, J. Leukoc. Biol., Oct 2002; 72: 819. Stanislaw M. Stepkowski, Blood, Jan 2002; 99: 680 - 689. Salvador Aznar Benitah, Mol. Biol. Cell, Jan 2003; 14: 40.
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total STAT5B protein.
Subcellular Location	Cytoplasm, Nucleus

Uniprot	P51692
Database Links	HGNC:11367 OMIM:245590 KEGG:hsa:6777 STRING:9606.ENSP00000293328 UniGene:Hs.595276
Function	Carries out a dual function
Pathway	Chemokine signaling pathway ErbB signaling pathway Jak-STAT signaling pathway Necroptosis Th1 and Th2 cell differentiation Th17 cell differentiation AGE-RAGE signaling pathway in diabetic complications
Protein Families	Transcription factor STAT family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC, WB ; ELISA ; IHC

Dilution

WB	1:500-1:3000
IHC	1:50-1:100

Tested Application

ELISA,WB,IHC;WB:1:500-1:3000,IHC:1:50-1:100

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10559099	CSB-PA100746	100ul	$297		Add to Cart

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