Protein phosphatase Slingshot homolog 3; SSH-3L; hSSH-3L;
Antigen
SSH3
Categories
Primary Antibodies
Clonality
polyclonal
Description
Protein phosphatase which may play a role in the regulation of actin filament dynamics. Can dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly By similarity.Niwa R., Cell 108:233-246(2002).Ohta Y., Genes Cells 8:811-824(2003).Ota T., Nat. Genet. 36:40-45(2004).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human SSH3.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Protein phosphatase which may play a role in the regulation of actin filament dynamics. Can dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly By similarity.
Niwa R., Cell 108:233-246(2002). Ohta Y., Genes Cells 8:811-824(2003). Ota T., Nat. Genet. 36:40-45(2004).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total SSH3 protein.
Protein phosphatase which may play a role in the regulation of actin filament dynamics. Can dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly (By similarity).
Pathway
Regulation of actin cytoskeleton
Protein Families
Protein-tyrosine phosphatase family
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.