BAP1 (BRCA1-associated protein 1) functions as a deubiquitinase that catalyzes the removal of ubiquitin from target proteins, and has roles in ubiquitin maturation, recycling, and editing activities. BAP1 has been shown to interact with the RING finger domain of BRCA1 and have overlapping subnuclear localization patterns. In studies in cancer, BAP1 protein can function both as a tumor suppressor and as a metastasis suppressor, thus is a valuable target of study.
Formulation
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
Immunogen
Recombinant Protein
Immunogen Region
Recombinant Protein
Isotype
IgG
Raised In
Rabbit
Shipping Condition
Ice packs
Species Reactivity
Human
Specificity
BAP1
Note
1:50-1:200
Clone No
IHC761
Purity
Purified
Storage
This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.