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Home / Primary Antibodies / IHC Antibodies

RAB11FIP3 Antibody

SKU : BHA10558612

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA441575
Alternative Names	Rab11-FIP3; EF hands-containing Rab-interacting protein; Eferin;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. Also required for the structural integrity of the endosomal recycling compartment during interphase. May play a role in breast cancer cell motility by regulating actin cytoskeleton.Prekeris R., J. Biol. Chem. 276:38966-38970(2001).Ishikawa K., DNA Res. 5:169-176(1998).Daniels R.J., Hum. Mol. Genet. 10:339-352(2001).
Host	Rabbit
Immunogen	Synthesized peptide derived from C-terminal of Human RAB11FIP3.
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. Also required for the structural integrity of the endosomal recycling compartment during interphase. May play a role in breast cancer cell motility by regulating actin cytoskeleton. Prekeris R., J. Biol. Chem. 276:38966-38970(2001). Ishikawa K., DNA Res. 5:169-176(1998). Daniels R.J., Hum. Mol. Genet. 10:339-352(2001).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total RAB11FIP3 protein.
Subcellular Location	Recycling endosome membrane, Peripheral membrane protein, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Cleavage furrow, Midbody

Uniprot	O75154
Database Links	HGNC:17224 OMIM:608738 KEGG:hsa:9727 STRING:9606.ENSP00000262305 UniGene:Hs.531642
Function	Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. Also required for the structural integrity of the endosomal recycling compartment during interphase. May play a role in breast cancer cell motility by regulating actin cytoskeleton. Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track)
Pathway	Endocytosis

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, IHC

Description

ELISA ; IHC, IHC ; ELISA

Dilution

IHC	1:50-1:100

Tested Application

ELISA,IHC;IHC:1:50-1:100

Datasheet
ELISA Protocol
Immunohistochemistry (IHC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558612	CSB-PA441575	100ul	$297		Add to Cart

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