Dopamine- and cAMP-regulated neuronal phosphoprotein; IPPD; Neuronal phosphoprotein DARPP-32; PPP1R1B;
Antigen
PPP1R1B
Categories
Primary Antibodies
Clonality
polyclonal
Description
Inhibitor of protein-phosphatase 1.JA Girault, J. Biol. Chem., Dec 1989; 264: 21748 - 21759.GL Snyder, J. Neurosci., Aug 1992; 12: 3071.Akinori Nishi, J. Neurosci., Nov 1997; 17: 8147.Artur Mayerhofer, J. Clin. Endocrinol. Metab., Dec 2000; 85: 4750 - 4757.
Host
Rabbit
Immunogen
Synthesized non-phosphopeptide derived from Human DARPP-32 around the phosphorylation site of threonine 75 (A-Y-T(p)-P-P).
Raised In
Rabbit
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Relevance
Inhibitor of protein-phosphatase 1.
JA Girault, J. Biol. Chem., Dec 1989; 264: 21748 - 21759. GL Snyder, J. Neurosci., Aug 1992; 12: 3071. Akinori Nishi, J. Neurosci., Nov 1997; 17: 8147. Artur Mayerhofer, J. Clin. Endocrinol. Metab., Dec 2000; 85: 4750 - 4757.
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total DARPP-32 protein.