Plays a critical role in endothelial cell capillary morphogenesis By similarity.St Croix B., Science 289:1197-1202(2000).Carson-Walter E.B., Cancer Res. 61:6649-6655(2001).Nanda A., Cancer Res. 64:8507-8511(2004)
Host
Rabbit
Immunogen
Synthesized peptide derived from Internal of Human PLXDC1.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Plays a critical role in endothelial cell capillary morphogenesis By similarity.
St Croix B., Science 289:1197-1202(2000). Carson-Walter E.B., Cancer Res. 61:6649-6655(2001). Nanda A., Cancer Res. 64:8507-8511(2004)
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total PLXDC1 protein.
Subcellular Location
Isoform 1: Cell membrane, Single-pass type I membrane protein, Cell junction, tight junction
Plays a critical role in endothelial cell capillary morphogenesis.
Protein Families
Plexin family
Tissue Specificity
Detected in endothelial cells from colorectal cancer, and in endothelial cells from primary cancers of the lung, liver, pancreas, breast and brain. Not detectable in endothelial cells from normal tissue. Expressed in fibrovascular membrane with increased
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.