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Home / Primary Antibodies / IHC Antibodies

Phospho-STK11 (S334) Antibody

SKU : BHA10541182

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA050179
Alternative Names	STK11; LKB1; PJS; Serine/threonine-protein kinase STK11; Liver kinase B1; LKB1; hLKB1; Renal carcinoma antigen NY-REN-19
Categories	Primary Antibodies ; Phospho Antibodies
Host	Rabbit
Immunogen	Synthesized peptide derived from Human LKB1 around the phosphorylation site of S334.
Involvement In Disease	Peutz-Jeghers syndrome (PJS); Testicular germ cell tumor (TGCT)
Isotype	IgG
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Species	Homo Sapiens (Human)
Subcellular Location	Nucleus, Cytoplasm, Membrane, Mitochondrion, Note=A small fraction localizes at membranes (By similarity), Relocates to the cytoplasm when bound to STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), Translocates to the mitochondrion during apoptosis, Translocates to the cytoplasm in response to metformin or peroxynitrite treatment, PTEN promotes cytoplasmic localization, SUBCELLULAR LOCATION: Isoform 2: Nucleus, Cytoplasm

Uniprot	Q15831
Database Links	HGNC:11389 OMIM:175200 KEGG:hsa:6794 STRING:9606.ENSP00000324856 UniGene:Hs.515005
Function	Tumor suppressor serine/threonine-protein kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response. Acts by phosphorylating the T-loop of AMPK family proteins, thus promoting their activity
Pathway	mTOR signaling pathway PI3K-Akt signaling pathway Autophagy MAPK Erk pathway Adipocytokine signaling pathway AMPK signaling FoxO signaling pathway
Protein Families	Protein kinase superfamily, CAMK Ser/Thr protein kinase family, LKB1 subfamily
Tissue Specificity	Ubiquitously expressed. Strongest expression in testis and fetal liver.

Buffer	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form	Liquid
Format	Liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications

IHC, ELISA

Description

IHC ; ELISA

Dilution

IHC	1:100-1:300
ELISA	1:10000

Tested Application

IHC,ELISA;IHC:1/100-1/300.ELISA:1/10000

Datasheet
Immunohistochemistry (IHC) Protocol
ELISA Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10541182	CSB-PA050179	100ug	$167		Add to Cart
BHA10541182	CSB-PA050179	50ug	$100		Add to Cart

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