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Home / Primary Antibodies / IHC Antibodies

Phospho-PIK3R1 (Y607) Antibody

BHA10542220
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+1 866.986.9598
Email
[email protected]
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Uniprot P27986
Database Links

HGNC:8979

OMIM:171833

KEGG:hsa:5295

STRING:9606.ENSP00000274335

UniGene:Hs.132225
Function Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling
Pathway cAMP signaling pathway Chemokine signaling pathway ErbB signaling pathway Estrogen signaling pathway HIF-1 signaling pathway Jak-STAT signaling pathway mTOR signaling pathway PI3K-Akt signaling pathway VEGF signaling pathway Focal adhesion Regulation of actin cytoskeleton TNF signaling pathway Apoptosis Autophagy Cellular senescence Ras signaling pathway Signaling pathways regulating pluripotency of stem cells B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Natural killer cell mediated cytotoxicity Osteoclast differentiation T cell receptor signaling pathway Toll-like receptor signaling pathway AGE-RAGE signaling pathway in diabetic complications AMPK signaling FoxO signaling pathway Insulin signaling pathway Phosphatidylinositol signaling system Phospholipase D signaling pathway Rap1 signaling pathway Sphingolipid signaling pathway Neurotrophin signaling pathway
Protein Families PI3K p85 subunit family
Tissue Specificity Isoform 2 is expressed in skeletal muscle and brain, and at lower levels in kidney and cardiac muscle. Isoform 2 and isoform 4 are present in skeletal muscle (at protein level).
Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form Liquid
Format Liquid
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications WB, IHC, ELISA
Description WB ; IHC ; ELISA, WB ; ELISA ; IHC
Dilution

WB1:500-1:2000
IHC1:100-1:300
ELISA1:10000
Tested Application WB,IHC,ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/10000
Datasheet
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
ELISA Protocol
SKU Supplier No. Size Your price Quantity
BHA10542220 CSB-PA000712 100ug $167
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BHA10542220 CSB-PA000712 50ug $100
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