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Home / Primary Antibodies / IHC Antibodies

Phospho-OXSR1 (Thr185) Antibody

SKU : BHA10560469

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA067482
Alternative Names	OXSR1; kinase OSR1; Oxidative-stress responsive 1;
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	polyclonal
Description	Oxidative-stress responsive 1 gene is located in the vicinity of three others genes - GOLGA4, ITGA9 and HYA22 on chromosome 3. These four genes are considered to be candidate tumor suppressors. Oxidative-stress responsive 1 protein has similarity to human Ste20/oxidant stress response kinase-1 and is thought to be involved in the response to oxidative stressTamari M., J. Hum. Genet. 44:116-120(1999).Kikuno R., DNA Res. 6-197-205(1999).The MGC Project Team; Genome Res. 14:2121-2127(2004).
Host	Rabbit
Immunogen	Peptide sequence around phosphorylation site of threonine185(R-K-T(p)-F-V) derived from Human OSR1.
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Oxidative-stress responsive 1 gene is located in the vicinity of three others genes - GOLGA4, ITGA9 and HYA22 on chromosome 3. These four genes are considered to be candidate tumor suppressors. Oxidative-stress responsive 1 protein has similarity to human Ste20/oxidant stress response kinase-1 and is thought to be involved in the response to oxidative stress Tamari M., J. Hum. Genet. 44:116-120(1999). Kikuno R., DNA Res. 6-197-205(1999). The MGC Project Team; Genome Res. 14:2121-2127(2004).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of OSR1 only when phosphorylated at threonine 185.
Subcellular Location	Cytoplasm

Uniprot	O95747
Database Links	HGNC:8508 OMIM:604046 KEGG:hsa:9943 STRING:9606.ENSP00000311713 UniGene:Hs.475970
Function	Regulates downstream kinases in response to environmental stress. May also have a function in regulating the actin cytoskeleton.
Protein Families	Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily
Tissue Specificity	Ubiquitously expressed in all tissue examined.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
Purity	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC, WB ; ELISA ; IHC

Dilution

WB	1:500-1:1000
IHC	1:50-1:100

Tested Application

ELISA,WB,IHC;WB:1:500-1:1000,IHC:1:50-1:100

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10560469	CSB-PA067482	100ul	$360		Add to Cart

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