Imprinted in placenta and liver protein; Tumor-suppressing subchromosomal transferable fragment candidate gene 3 protein; Tumor-suppressing STF cDNA 3 protein; Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene C protein; p17-Beckwith-Wiedema
Antigen
PHLDA2
Categories
Primary Antibodies
Clonality
polyclonal
Description
Plays a role in regulating placenta growth. May act via its PH domain that competes with other PH domain-containing proteins, thereby preventing their binding to membrane lipids By similarity.Hu R.-J., Genomics 46:9-17(1997).Qian N., Hum. Mol. Genet. 6:2021-2029(1997).Schwienbacher C., Proc. Natl. Acad. Sci. U.S.A. 95:3873-3878(1998).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human PHLA2.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Plays a role in regulating placenta growth. May act via its PH domain that competes with other PH domain-containing proteins, thereby preventing their binding to membrane lipids By similarity.
Hu R.-J., Genomics 46:9-17(1997). Qian N., Hum. Mol. Genet. 6:2021-2029(1997). Schwienbacher C., Proc. Natl. Acad. Sci. U.S.A. 95:3873-3878(1998).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total PHLA2 protein.
Plays a role in regulating placenta growth. May act via its PH domain that competes with other PH domain-containing proteins, thereby preventing their binding to membrane lipids (By similarity).
Protein Families
PHLDA2 family
Tissue Specificity
Expressed in placenta and adult prostate gland. In placenta, it is present in all cells of the villous cytotrophoblast. The protein is absent in cells from hydatidiform moles. Hydatidiform mole is a gestation characterized by abnormal development of both
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.