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Home / Primary Antibodies / IHC Antibodies

PE/TR Anti-Mouse CD162 Antibody[4RA10]

SKU : BHA10327560

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	E-AB-F1034P
Background	The 4RA10 antibody reacts with the N-terminal functional peptide of CD162 (P-selectin glycoprotein ligand-1, PSGL-1), encoded by the Selpl gene. PSGL-1 is expressed on the cell surface as a homodimer of approximately 230 kDa. In the mouse, Selpl mRNA is detected in most tissues, with high levels found in hematopoietic cells, brain, and adipose tissue. Flow cytometric analyses have revealed CD162 expression on bone marrow-derived mast and dendritic cells, splenic leukocytes, platelets, peripheral blood neutrophils, and neutrophil and T-cell lines. PSGL-1 is a ligand for P-selectin (CD62P) and is involved in leukocyte rolling, the migration of leukocytes into inflamed tissues, and responses to vascular injury. It is a sialomucin that must be specifically sialylated, fucosylated, and sulfated to bind P-selectin. There is also evidence that other ligands for PSGL-1 and CD62P may exist. 4RA10 mAb is reported to block the binding of mouse leukocytes to CD62P and CD62L.
Categories	Primary Antibodies;Primary Antibodies///Flow Cytomerty(FACS)
Clonality	Monoclonal
Host	Rat
Isotype	Rat IgG1, k
Reactivity	Mouse
Synonyms	P-selectin glycoprotein ligand 1,Selplg,PSGL-1,Selectin P ligand,CD162

Swissprot	Q62170
Accession Number	20345
Gene Id	20345
Clone No	4RA10

Buffer	PBS with 0.05% Proclin300, 1% BSA
Storage	Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Applications	FCM

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SKU	Supplier No.	Size	Your price	Quantity
BHA10327560	E-AB-F1034P	20Tests	$115		Add to Cart
BHA10327560	E-AB-F1034P	50Tests	$180		Add to Cart
BHA10327560	E-AB-F1034P	100Tests	$285		Add to Cart
BHA10327560	E-AB-F1034P	200Tests	$425		Add to Cart

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