JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Primary Antibodies / IHC Antibodies

PDPK1 (Ab-241) Antibody

SKU : BHA10559607

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

CUSABIO TECHONOLOGY LLC

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	CSB-PA088763
Alternative Names	PDPK1, PkB kinase, Protein kinase B kinase, hPDK1, kinase PDK1
Categories	Primary Antibodies
Clonality	polyclonal
Description	Phosphorylates and activates not only PKB/AKT, but also PKA, PKC-zeta, RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development Scheid MP,et al. (2005)Mol Cell Biol; 25(6): 2347-63Chen H, et al. (2001) Biochemistry; 40(39): 11851-9Sato S,et al. (2002) J Biol Chem; 277(42): 39360-7Lim MA, et al.(2003)Proc Natl Acad Sci U S A; 100(24): 14006-11Beausoleil SA, et al. (2004)Proc Natl Acad Sci U S A; 101(33): 12130-5
Host	Rabbit
Immunogen	Peptide sequence around aa.239~243 (A-N-S-F-V) derived from Human PDK1.
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Phosphorylates and activates not only PKB/AKT, but also PKA, PKC-zeta, RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development Scheid MP,et al. (2005)Mol Cell Biol; 25(6): 2347-63 Chen H, et al. (2001) Biochemistry; 40(39): 11851-9 Sato S,et al. (2002) J Biol Chem; 277(42): 39360-7 Lim MA, et al.(2003)Proc Natl Acad Sci U S A; 100(24): 14006-11 Beausoleil SA, et al. (2004)Proc Natl Acad Sci U S A; 101(33): 12130-5
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous level of total PDK1 protein.
Subcellular Location	Cytoplasm, Nucleus, Cell membrane, Peripheral membrane protein, Cell junction, focal adhesion

Uniprot	O15530
Database Links	HGNC:8816 OMIM:605213 KEGG:hsa:5170 STRING:9606.ENSP00000344220 UniGene:Hs.459691
Function	Serine/threonine kinase which acts as a master kinase, phosphorylating and activating a subgroup of the AGC family of protein kinases. Its targets include
Pathway	mTOR signaling pathway PI3K-Akt signaling pathway PPAR signaling pathway Focal adhesion Apoptosis Autophagy Fc epsilon RI signaling pathway T cell receptor signaling pathway AMPK signaling FoxO signaling pathway Insulin signaling pathway Sphingolipid signaling pathway Neurotrophin signaling pathway
Protein Families	Protein kinase superfamily, AGC Ser/Thr protein kinase family, PDPK1 subfamily
Tissue Specificity	Appears to be expressed ubiquitously. The Tyr-9 phosphorylated form is markedly increased in diseased tissue compared with normal tissue from lung, liver, colon and breast.

Buffer	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Purity	Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IHC, IF

Description

ELISA ; WB ; IHC ; IF, WB ; ELISA ; IHC ; IF

Dilution

WB	1:500-1:1000
IHC	1:50-1:200
IF	1:100-1:200

Tested Application

ELISA,WB,IHC,IF;WB:1:500-1:1000,IHC:1:50-1:200,IF:1:100-1:200

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHA10559607	CSB-PA088763	100ul	$297		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2024 Biohippo. All rights reserved.