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Home / Primary Antibodies / IHC Antibodies

OSGEP Antibody

SKU : BHA10520057

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA878842ESR1HU
Alternative Names	Probable tRNA N6-adenosine threonylcarbamoyltransferase (EC 2.3.1.234) (N6-L-threonylcarbamoyladenine synthase) (t(6)A synthase) (O-sialoglycoprotein endopeptidase) (hOSGEP) (t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEP) (tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP), OSGEP, GCPL1
Antigen	OSGEP
Categories	Primary Antibodies
Clonality	polyclonal
Conjugate	Non-conjugated
Description	Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
Host	Rabbit
Immunogen	Recombinant Human Probable tRNA N6-adenosine threonylcarbamoyltransferase protein (1-335AA)
Isotype	IgG
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
Species	Homo Sapiens (Human)
Subcellular Location	Cytoplasm, Nucleus

Uniprot	Q9NPF4
Database Links	HGNC:18028 OMIM:610107 KEGG:hsa:55644 STRING:9606.ENSP00000206542 UniGene:Hs.525196
Function	Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
Protein Families	KAE1 / TsaD family
Research Area	Epigenetics and Nuclear Signaling
Tissue Specificity	Widely expressed at low level. Expressed in heart, placenta, liver, kidney, lung, brain, skeletal muscle and pancreas.

Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form	Liquid
Format	Liquid
Purification	Antigen Affinity Purified
Purity	Antigen Affinity Purified
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC, WB ; ELISA ; IHC

Dilution

WB	1:1000-1:5000
IHC	1:20-1:200

Tested Application

ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10520057	CSB-PA878842ESR1HU	100ul	$299		Add to Cart
BHA10520057	CSB-PA878842ESR1HU	50ul	$166		Add to Cart

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