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Home / Primary Antibodies / IHC Antibodies

NET1 Antibody

SKU : BHA10557183

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA015714KA01HU
Alternative Names	NET1;ARHGEF8;NET1A
Categories	Primary Antibodies
Description	This gene is part of the family of Rho guanine nucleotide exchange factors. Members of this family activate Rho proteins by catalyzing the exchange of GDP for GTP. The protein encoded by this gene interacts with RhoA within the cell nucleus and may play a role in repairing DNA damage after ionizing radiation. Pseudogenes of this gene are located on the long arms of chromosomes 1, 7 and 18. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
Hgnc	11051
Host	Rabbit
Immunogen	Recombinant protein of human NET1
Intended Use	For research use only. Not for human, diagnostic or therapeutic use.
Isotype	IgG
Mgi	105090, 105090
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	This gene is part of the family of Rho guanine nucleotide exchange factors. Members of this family activate Rho proteins by catalyzing the exchange of GDP for GTP. The protein encoded by this gene interacts with RhoA within the cell nucleus and may play a role in repairing DNA damage after ionizing radiation. Pseudogenes of this gene are located on the long arms of chromosomes 1, 7 and 18. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
Size	100μl(100μg)
Species	Homo Sapiens (Human)
Subcellular Location	Cytoplasm, Nucleus

Rgd	621824
Uniprot	Q7Z628
Gene Id	10276, 10276
Database Links	HGNC:14592 OMIM:606450 KEGG:hsa:10276 STRING:9606.ENSP00000347134 UniGene:Hs.25155
Function	Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death.
Research Area	Signal Transduction, Signal Transduction
Tissue Specificity	Widely expressed.
Weight	65, 65

Buffer	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Format	liquid
Purification	Affinity purification
Purity	Affinity purification
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer	Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3., Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Applications

ELISA, WB, WB, IHC

Description

ELISA ; WB ; IHC, WB ; ELISA ; IHC

Dilution

WB	1:500-1:2000
IHC	1:50-1:200

Tested Application

ELISA,WB,IHC;WB:1:500-1:2000,IHC:1:50-1:200

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557183	CSB-PA015714KA01HU	100μl	$387.33		Add to Cart

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