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Home / Primary Antibodies / IHC Antibodies

MT-ND1 Antibody

SKU : BHA10559527

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA267250
Alternative Names	NADH-ubiquinone oxidoreductase chain 1; EC 1.6.5.3; NADH dehydrogenase subunit 1; MT-ND1; MTND1
Categories	Primary Antibodies
Clonality	polyclonal
Description	Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone By similarity. HAMAP-Rule MF_01350Anderson S., Nature 290:457-465(1981).Horai S., Proc. Natl. Acad. Sci. U.S.A. 92:532-536(1995).Moilanen J.S., Mol. Biol. Evol. 20:2132-2142(2003).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human MT-ND1.
Involvement In Disease	Leber hereditary optic neuropathy (LHON); Mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes syndrome (MELAS); Alzheimer disease mitochondrial (AD-MT); Diabetes mellitus, non-insulin-dependent (NIDDM); Mitochondrial complex I deficiency (MT-C1D)
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone By similarity. HAMAP-Rule MF_01350 Anderson S., Nature 290:457-465(1981). Horai S., Proc. Natl. Acad. Sci. U.S.A. 92:532-536(1995). Moilanen J.S., Mol. Biol. Evol. 20:2132-2142(2003).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total MT-ND1 protein.
Subcellular Location	Mitochondrion inner membrane, Multi-pass membrane protein

Uniprot	P03886
Database Links	HGNC:7455 OMIM:125853 KEGG:hsa:4535 STRING:9606.ENSP00000354687
Function	Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
Pathway	Oxidative Phosphorylation
Protein Families	Complex I subunit 1 family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC, WB ; ELISA ; IHC

Dilution

WB	1:500-1:3000
IHC	1:50-1:100

Tested Application

ELISA,WB,IHC;WB:1:500-1:3000,IHC:1:50-1:100

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10559527	CSB-PA267250	100ul	$297		Add to Cart

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