JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Primary Antibodies / IHC Antibodies

MCL1 Antibody

SKU : BHA10559755

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

CUSABIO TECHONOLOGY LLC

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	CSB-PA787977
Alternative Names	EAT/MCL-1 protein; Induced myeloid leukemia cell differentiation protein Mcl-1; Myeloid cell leukemia sequence 1.;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.Alfredo De Biasio, J. Biol. Chem., Jun 2007; 10.1074.Potchanapond Graidist, J. Biol. Chem., Sep 2004; 279: 40868 - 40875. Kenichi Fujise, J. Biol. Chem., Dec 2000; 275: 39458. Di Zhang, J. Biol. Chem., Sep 2002; 277: 37430 - 37438.
Host	Rabbit
Immunogen	Synthesized peptide derived from Human MCL1.
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis. Alfredo De Biasio, J. Biol. Chem., Jun 2007; 10.1074. Potchanapond Graidist, J. Biol. Chem., Sep 2004; 279: 40868 - 40875. Kenichi Fujise, J. Biol. Chem., Dec 2000; 275: 39458. Di Zhang, J. Biol. Chem., Sep 2002; 277: 37430 - 37438.
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total MCL1 protein.
Subcellular Location	Membrane, Single-pass membrane protein, Cytoplasm, Mitochondrion, Nucleus, nucleoplasm

Uniprot	Q07820
Database Links	HGNC:6943 OMIM:159552 KEGG:hsa:4170 STRING:9606.ENSP00000358022 UniGene:Hs.632486
Function	Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.
Pathway	Jak-STAT signaling pathway PI3K-Akt signaling pathway Apoptosis
Protein Families	Bcl-2 family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC, WB ; ELISA ; IHC

Dilution

WB	1:500-1:3000
IHC	1:50-1:100

Tested Application

ELISA,WB,IHC;WB:1:500-1:3000,IHC:1:50-1:100

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHA10559755	CSB-PA787977	100ul	$297		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2024 Biohippo. All rights reserved.