Component of a protein kinase signal transduction cascade. Activates the JNK, but not ERK or p38 kinase pathways.Takeda K., J. Biol. Chem. 282:7522-7531(2007).Gregory S.G., Nature 441:315-321(2006).Wang X.S., Biochem. Biophys. Res. Commun. 253:33-37(1998).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human MAP3K6.
Raised In
Rabbit
Reactivity
Human, Mouse
Regulatory
RUO
Relevance
Component of a protein kinase signal transduction cascade. Activates the JNK, but not ERK or p38 kinase pathways.
Takeda K., J. Biol. Chem. 282:7522-7531(2007). Gregory S.G., Nature 441:315-321(2006). Wang X.S., Biochem. Biophys. Res. Commun. 253:33-37(1998).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total MAP3K6 protein.