Keratin type II cytoskeletal 7; Cytokeratin-7; CK-7; K7; Sarcolectin
Categories
Primary Antibodies
Clonality
polyclonal
Description
Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).M Rosenberg, Mol. Cell. Biol., Feb 1988; 8: 722 - 736.SM Troyanovsky, J. Cell Sci., Jul 1989; 93: 419.Kevin M. McGowan, Genes & Dev., Jun 2002; 16: 1412.Nicholas Bianchi, Mol. Cell. Biol., Aug 2005; 25: 7249 - 7259.
Host
Rabbit
Immunogen
Synthesized peptide derived from Human Keratin 7.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).
M Rosenberg, Mol. Cell. Biol., Feb 1988; 8: 722 - 736. SM Troyanovsky, J. Cell Sci., Jul 1989; 93: 419. Kevin M. McGowan, Genes & Dev., Jun 2002; 16: 1412. Nicholas Bianchi, Mol. Cell. Biol., Aug 2005; 25: 7249 - 7259.
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total Keratin 7 protein.
Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).
Protein Families
Intermediate filament family
Tissue Specificity
Expressed in cultured epidermal, bronchial and mesothelial cells but absent in colon, ectocervix and liver. Observed throughout the glandular cells in the junction between stomach and esophagus but is absent in the esophagus.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.