Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'.Akira Ikari, Chiaki Okude, Hayato Sawada, et al. (2008) Down-regulation of TRPM6-mediated magnesium influx by cyclosporin A Naunyn-Schmiedeberg's Archives of Pharmacology, 377(4-6):333-43.This article references the use of the #21021 in the following applications :Western blotting
Host
Rabbit
Immunogen
Peptide sequence around aa.89~93 (T-T-T-P-T) derived from Human c-Jun.
Raised In
Rabbit
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Relevance
Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'.Akira Ikari, Chiaki Okude, Hayato Sawada, et al. (2008) Down-regulation of TRPM6-mediated magnesium influx by cyclosporin A Naunyn-Schmiedeberg's Archives of Pharmacology, 377(4-6):333-43.This article references the use of the JUN (Ab-91) Antibody in the following applications :Western blotting
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous level of total c-Jun protein.
Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Purity
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.