Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'.Boyle W J, et al. (1991) Cell. 64(3): 573-584.Binetruy B, et al. (1991) Nature. 351: 122-127.Smeal T, et al. (1991) Nature. 354:494-496.Derijard B, et al. (1994) Cell. 76:1025-1037.Kyriakis J M, et al. (1994) Nature. 369: 156-160.
Host
Rabbit
Immunogen
Peptide sequence around aa.237~241 (G-E-T-P-P) derived from Human c-Jun.
Raised In
Rabbit
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Relevance
Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'.
Boyle W J, et al. (1991) Cell. 64(3): 573-584. Binetruy B, et al. (1991) Nature. 351: 122-127. Smeal T, et al. (1991) Nature. 354:494-496. Derijard B, et al. (1994) Cell. 76:1025-1037. Kyriakis J M, et al. (1994) Nature. 369: 156-160.
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous level of total c-Jun protein.
Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Purity
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.