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Home / Primary Antibodies / IHC Antibodies

IRX3 Antibody

SKU : BHA10557888

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA090661
Alternative Names	iroquois homeobox 3; IRX-1;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells By similarity.Hansen L., Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.The MGC Project Team, Genome Res. 14:2121-2127(2004).Lewis M.T., Submitted (MAR-1997) to the EMBL/GenBank/DDBJ databases.
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human IRX3.
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells By similarity. Hansen L., Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases. The MGC Project Team, Genome Res. 14:2121-2127(2004). Lewis M.T., Submitted (MAR-1997) to the EMBL/GenBank/DDBJ databases.
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total IRX3 protein.
Subcellular Location	Nucleus

Uniprot	P78415
Database Links	HGNC:14360 OMIM:612985 KEGG:hsa:79191 STRING:9606.ENSP00000331608 UniGene:Hs.499205
Function	Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells (By similarity).
Protein Families	TALE/IRO homeobox family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, IHC

Description

ELISA ; IHC, IHC ; ELISA

Dilution

IHC	1:50-1:100

Tested Application

ELISA,IHC;IHC:1:50-1:100

Datasheet
ELISA Protocol
Immunohistochemistry (IHC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557888	CSB-PA090661	100ul	$297		Add to Cart

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