HMG17; high mobility group protein N2; high-mobility group (nonhistone chromosomal) protein 17; high-mobility group nucleosomal binding domain 2; high-mobility group nucleosome binding domain 2
Antigen
HMGN2
Categories
Primary Antibodies
Clonality
polyclonal
Description
Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation By similarity.Landsman D., J. Biol. Chem. 261:7479-7484(1986).Gregory S.G., Nature 441:315-321(2006).Giancotti V., Eur. J. Biochem. 198:211-216(1991).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human HMG17.
Raised In
Rabbit
Reactivity
Human, Mouse
Regulatory
RUO
Relevance
Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation By similarity.
Landsman D., J. Biol. Chem. 261:7479-7484(1986). Gregory S.G., Nature 441:315-321(2006). Giancotti V., Eur. J. Biochem. 198:211-216(1991).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total HMG17 protein.
Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation (By similarity).
Protein Families
HMGN family
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.