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Home / Primary Antibodies / IHC Antibodies

GRM8 Antibody

SKU : BHA10559741

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA232728
Alternative Names	GPRC1H; MGLUR8; mGlu8; GLUTAMATE RECEPTOR; METABOTROPIC
Categories	Primary Antibodies
Clonality	polyclonal
Description	G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.Patrick. M. Downey, J Biomol Screen, Dec 2005; 10: 841 - 848.RJ Wenthold, J. Biol. Chem., Jan 1994; 269: 1332 - 1339.Toshiaki Watanabe, Cancer Res., Oct 2006; 66: 9804 - 9808.V. Bruno, J. Neurosci., Sep 2000; 20: 6413.
Host	Rabbit
Immunogen	Synthesized peptide derived from Human GluR8.
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Patrick. M. Downey, J Biomol Screen, Dec 2005; 10: 841 - 848. RJ Wenthold, J. Biol. Chem., Jan 1994; 269: 1332 - 1339. Toshiaki Watanabe, Cancer Res., Oct 2006; 66: 9804 - 9808. V. Bruno, J. Neurosci., Sep 2000; 20: 6413.
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total GluR8 protein.
Subcellular Location	Cell membrane, Multi-pass membrane protein

Uniprot	O00222
Database Links	HGNC:4600 OMIM:601116 KEGG:hsa:2918 STRING:9606.ENSP00000344173 UniGene:Hs.449625
Function	G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
Pathway	Oxidative Phosphorylation Phospholipase D signaling pathway Glutamatergic synapse
Protein Families	G-protein coupled receptor 3 family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC, WB ; ELISA ; IHC

Dilution

WB	1:500-1:3000
IHC	1:50-1:100

Tested Application

ELISA,WB,IHC;WB:1:500-1:3000,IHC:1:50-1:100

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10559741	CSB-PA232728	100ul	$297		Add to Cart

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