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Home / Primary Antibodies / IHC Antibodies

GRM4 Antibody

SKU : BHA10559738

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA693203
Alternative Names	Metabotropic glutamate receptor 4; mGluR4; GPRC1D; MGLUR4; GRM4
Categories	Primary Antibodies
Clonality	polyclonal
Description	G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.Susana Santos Correia, J. Biol. Chem., Feb 2003; 278: 6307 - 6313.Maxim Mokin, J Neurophysiol, Jan 2006; 95: 215 - 224.Maxim Mokin, J Neurophysiol, Jan 2006; 95: 215 - 224.Peyman Golshani, PNAS, Mar 2001; 98: 4172.
Host	Rabbit
Immunogen	Synthesized peptide derived from Human GluR4.
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity. Susana Santos Correia, J. Biol. Chem., Feb 2003; 278: 6307 - 6313. Maxim Mokin, J Neurophysiol, Jan 2006; 95: 215 - 224. Maxim Mokin, J Neurophysiol, Jan 2006; 95: 215 - 224. Peyman Golshani, PNAS, Mar 2001; 98: 4172.
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total GluR4 protein.
Subcellular Location	Cell membrane, Multi-pass membrane protein

Uniprot	Q14833
Database Links	HGNC:4596 OMIM:604100 KEGG:hsa:2914 STRING:9606.ENSP00000363296 UniGene:Hs.429018
Function	G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
Pathway	Oxidative Phosphorylation Phospholipase D signaling pathway Glutamatergic synapse
Protein Families	G-protein coupled receptor 3 family
Tissue Specificity	Strongly expressed in the cerebellum. Expressed at low levels in hippocampus, hypothalamus and thalamus. No expression detected in liver.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC, WB ; ELISA ; IHC

Dilution

WB	1:500-1:3000
IHC	1:50-1:100

Tested Application

ELISA,WB,IHC;WB:1:500-1:3000,IHC:1:50-1:100

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10559738	CSB-PA693203	100ul	$297		Add to Cart

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