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Home / Primary Antibodies / IHC Antibodies

GAK Antibody

SKU : BHA10557757

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA100194
Alternative Names	Cyclin G-associated kinase; EC 2.7.11.1; kinase GAK;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1.Kimura S.H., Genomics 44:179-187(1997).The MGC Project Team; Genome Res. 14:2121-2127(2004).Greener T., J. Biol. Chem. 275:1365-1370(2000).
Host	Rabbit
Immunogen	Synthesized peptide derived from Internal of Human GAK.
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1. Kimura S.H., Genomics 44:179-187(1997). The MGC Project Team; Genome Res. 14:2121-2127(2004). Greener T., J. Biol. Chem. 275:1365-1370(2000).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total GAK protein.
Subcellular Location	Cytoplasm, perinuclear region, Golgi apparatus, trans-Golgi network, Cell junction, focal adhesion

Uniprot	O14976
Database Links	HGNC:4113 OMIM:602052 KEGG:hsa:2580 STRING:9606.ENSP00000314499 UniGene:Hs.369607
Function	Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1.
Protein Families	Protein kinase superfamily, Ser/Thr protein kinase family
Tissue Specificity	Ubiquitous. Highest in testis.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC, WB ; ELISA ; IHC

Dilution

WB	1:500-1:3000
IHC	1:50-1:200

Tested Application

ELISA,WB,IHC;WB:1:500-1:3000,IHC:1:50-1:200

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557757	CSB-PA100194	100ul	$297		Add to Cart

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