JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Primary Antibodies / IHC Antibodies

GAB2 (Ab-159) Antibody

SKU : BHA10559705

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

CUSABIO TECHONOLOGY LLC

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	CSB-PA781252
Alternative Names	GABJ; GRB2-associated binding protein 2; KIAA0571; pp100;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.Nishida K., Blood 93:1809-1816(1999).Nagase T., DNA Res. 5:31-39(1998).Taylor T.D., Nature 440:497-500(2006).
Host	Rabbit
Immunogen	Synthesized non-phosphopeptide derived from Human GRB2 around the phosphorylation site of serine 159 (K-S-S(p)-A-P).
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis. Nishida K., Blood 93:1809-1816(1999). Nagase T., DNA Res. 5:31-39(1998). Taylor T.D., Nature 440:497-500(2006).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total GRB2 protein.
Subcellular Location	Cytoplasm, Cell membrane

Uniprot	Q9UQC2
Database Links	HGNC:14458 OMIM:606203 KEGG:hsa:9846 STRING:9606.ENSP00000354952 UniGene:Hs.429434
Function	Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.
Pathway	Ras signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Osteoclast differentiation Phospholipase D signaling pathway Sphingolipid signaling pathway
Protein Families	GAB family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC, WB ; ELISA ; IHC

Dilution

WB	1:500-1:3000
IHC	1:50-1:100

Tested Application

ELISA,WB,IHC;WB:1:500-1:3000,IHC:1:50-1:100

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHA10559705	CSB-PA781252	100ul	$297		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2024 Biohippo. All rights reserved.