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Home / Primary Antibodies / IHC Antibodies

FGF3 Antibody

SKU : BHA10558917

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA266668
Alternative Names	INT2; HBGF-3
Categories	Primary Antibodies
Clonality	polyclonal
Description	The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its similarity with mouse fgf3/int-2, a proto-oncogene activated in virally induced mammary tumors in the mouse. Frequent amplification of this gene has been found in human tumors, which may be important for neoplastic transformation and tumor progression. Studies of the similar genes in mouse and chicken suggested the role in inner ear formation.
Host	Rabbit
Immunogen	Synthetic peptide corresponding to residues near the C terminal of Human fibroblast growth factor 3
Involvement In Disease	Deafness with labyrinthine aplasia, microtia and microdontia (LAMM)
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its similarity with mouse fgf3/int-2, a proto-oncogene activated in virally induced mammary tumors in the mouse. Frequent amplification of this gene has been found in human tumors, which may be important for neoplastic transformation and tumor progression. Studies of the similar genes in mouse and chicken suggested the role in inner ear formation.
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total FGF3 protein.
Subcellular Location	Secreted

Uniprot	P11487
Database Links	HGNC:3681 OMIM:164950 KEGG:hsa:2248 STRING:9606.ENSP00000334122 UniGene:Hs.37092
Function	Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. Required for normal ear development.
Pathway	MAPK signaling pathway PI3K-Akt signaling pathway Regulation of actin cytoskeleton Ras signaling pathway Rap1 signaling pathway
Protein Families	Heparin-binding growth factors family

Buffer	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Form	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Format	liquid
Purification	Antigen Affinity Purified
Purity	Antigen Affinity Purified
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, IHC

Description

ELISA ; IHC, IHC ; ELISA

Dilution

IHC	1:50-1:100

Tested Application

ELISA,IHC;IHC:1:50-1:100

Datasheet
ELISA Protocol
Immunohistochemistry (IHC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558917	CSB-PA266668	100ul	$297		Add to Cart

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