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Home / Primary Antibodies / IHC Antibodies

ERF Antibody

SKU : BHA10557864

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA447319
Alternative Names	ETS-domain transcription factor ERF; Ets2 repressor factor;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Potent transcriptional repressor that binds to the H1 element of the Ets2 promoter. May regulate other genes involved in cellular proliferation. Required for extraembryonic ectoderm differentiation, ectoplacental cone cavity closure, and chorioallantoic attachment By similarity. May be important for regulating trophoblast stem cell differentiation By similarity.Sgouras D.N., EMBO J. 14:4781-4793(1995).Grimwood J., Nature 428:529-535(2004).Olsen J.V., Cell 127:635-648(2006).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human ERF.
Involvement In Disease	Craniosynostosis 4 (CRS4); Chitayat syndrome (CHYTS)
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Potent transcriptional repressor that binds to the H1 element of the Ets2 promoter. May regulate other genes involved in cellular proliferation. Required for extraembryonic ectoderm differentiation, ectoplacental cone cavity closure, and chorioallantoic attachment By similarity. May be important for regulating trophoblast stem cell differentiation By similarity. Sgouras D.N., EMBO J. 14:4781-4793(1995). Grimwood J., Nature 428:529-535(2004). Olsen J.V., Cell 127:635-648(2006).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total ERF protein.
Subcellular Location	Nucleus

Uniprot	P50548
Database Links	HGNC:3444 OMIM:600775 KEGG:hsa:2077 STRING:9606.ENSP00000222329 UniGene:Hs.655969
Function	Potent transcriptional repressor that binds to the H1 element of the Ets2 promoter. May regulate other genes involved in cellular proliferation. Required for extraembryonic ectoderm differentiation, ectoplacental cone cavity closure, and chorioallantoic attachment (By similarity). May be important for regulating trophoblast stem cell differentiation (By similarity).
Protein Families	ETS family
Tissue Specificity	Highest levels in testis, ovary, pancreas, and heart.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, IHC

Description

ELISA ; IHC, IHC ; ELISA

Dilution

IHC	1:50-1:100

Tested Application

ELISA,IHC;IHC:1:50-1:100

Datasheet
ELISA Protocol
Immunohistochemistry (IHC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557864	CSB-PA447319	100ul	$297		Add to Cart

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