Elongation of very long chain fatty acids protein 3; Cold-inducible glycoprotein of 30 kDa;
Antigen
ELOVL3
Categories
Primary Antibodies
Clonality
polyclonal
Description
Condensing enzyme that elongates saturated and monounsaturated very long chain fatty acids (VLCFAs). Highest activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs.The MGC Project Team; Genome Res. 14:2121-2127(2004).Semina E.V., Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases.
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human ELOVL3.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Condensing enzyme that elongates saturated and monounsaturated very long chain fatty acids (VLCFAs). Highest activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs.
The MGC Project Team; Genome Res. 14:2121-2127(2004). Semina E.V., Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases.
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total ELOVL3 protein.
Subcellular Location
Endoplasmic reticulum membrane, Multi-pass membrane protein
Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18
Protein Families
ELO family, ELOVL3 subfamily
Tissue Specificity
Testis.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.