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Home / Primary Antibodies / IHC Antibodies

CXCL14 Antibody

SKU : BHA10550506

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA576532
Alternative Names	chemokine (C-X-C motif) ligand 14
Categories	Primary Antibodies
Description	This gene belongs to the cytokine gene family which encode secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC (Cys-X-Cys) subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages. It has been implicated that this cytokine is involved in the homeostasis of monocyte-derived macrophages rather than in inflammation.
Host	Rabbit
Immunogen	Fusion protein of Human CXCL14
Isotype	IgG
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	This gene belongs to the cytokine gene family which encode secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC (Cys-X-Cys) subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages. It has been implicated that this cytokine is involved in the homeostasis of monocyte-derived macrophages rather than in inflammation.
Species	Homo Sapiens (Human)
Subcellular Location	Secreted

Uniprot	O95715
Database Links	HGNC:10640 OMIM:604186 KEGG:hsa:9547 STRING:9606.ENSP00000337065 UniGene:Hs.483444
Function	Potent chemoattractant for neutrophils, and weaker for dendritic cells. Not chemotactic for T-cells, B-cells, monocytes, natural killer cells or granulocytes. Does not inhibit proliferation of myeloid progenitors in colony formation assays.
Pathway	Chemokine signaling pathway
Protein Families	Intercrine alpha (chemokine CxC) family
Tissue Specificity	Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Highly expressed in normal tissue without inflammatory stimuli and infrequently expressed in cancer cell lines. Weakly expressed in monocyte-derived dendritic cells. N

Buffer	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form	Liquid
Format	Liquid
Purification	Antigen affinity purification
Purity	Antigen affinity purification
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Applications

ELISA, IHC

Description

ELISA ; IHC, IHC ; ELISA

Dilution

ELISA	1:2000-1:5000
IHC	1:50-1:200

Tested Application

ELISA,IHC;ELISA:1:2000-1:5000,IHC:1:50-1:200

Datasheet
ELISA Protocol
Immunohistochemistry (IHC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10550506	CSB-PA576532	100ul	$299		Add to Cart
BHA10550506	CSB-PA576532	50ul	$166		Add to Cart

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