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Home / Primary Antibodies / IHC Antibodies

CSNK1A1 Antibody

SKU : BHA10559816

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA833830
Alternative Names	CK1-alpha; CKI-alpha; CSNK1A1; Casein kinase I; alpha isoform
Categories	Primary Antibodies
Clonality	polyclonal
Description	Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis.Tapia C., FEBS Lett. 349:307-312(1994).Fish K.J., J. Biol. Chem. 270:14875-14883(1995).Liu C., Cell 108:837-847(2002).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human CKI-α.
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis. Tapia C., FEBS Lett. 349:307-312(1994). Fish K.J., J. Biol. Chem. 270:14875-14883(1995). Liu C., Cell 108:837-847(2002).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total CKI-α protein.
Subcellular Location	Cytoplasm, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Chromosome, centromere, kinetochore, Nucleus speckle, Cytoplasm, cytoskeleton, cilium basal body

Uniprot	P48729
Database Links	HGNC:2451 OMIM:600505 KEGG:hsa:1452 UniGene:Hs.529862
Function	Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis
Pathway	Hedgehog signaling pathway Wnt signaling pathway
Protein Families	Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IHC, IF

Description

ELISA ; WB ; IHC ; IF, WB ; ELISA ; IHC ; IF

Dilution

WB	1:500-1:3000
IHC	1:50-1:100
IF	1:100-1:500

Tested Application

ELISA,WB,IHC,IF;WB:1:500-1:3000,IHC:1:50-1:100,IF:1:100-1:500

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10559816	CSB-PA833830	100ul	$297		Add to Cart

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