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Home / Primary Antibodies / IHC Antibodies

CSGALNACT1 Antibody

SKU : BHA10558340

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA953607
Alternative Names	Chondroitin ;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. Important role in chondroitin chain biosynthesis in cartilage.Uyama T., J. Biol. Chem. 277:8841-8846(2002).Gotoh M., J. Biol. Chem. 277:38189-38196(2002).Clark H.F., Genome Res. 13:2265-2270(2003).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human CSGALNACT1.
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. Important role in chondroitin chain biosynthesis in cartilage. Uyama T., J. Biol. Chem. 277:8841-8846(2002). Gotoh M., J. Biol. Chem. 277:38189-38196(2002). Clark H.F., Genome Res. 13:2265-2270(2003).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total CSGALNACT1 protein.
Subcellular Location	Golgi apparatus, Golgi stack membrane, Single-pass type II membrane protein

Uniprot	Q8TDX6
Database Links	HGNC:24290 OMIM:616615 KEGG:hsa:55790 STRING:9606.ENSP00000310891 UniGene:Hs.613729
Function	Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. Important role in chondroitin chain biosynthesis in cartilage formation and subsequent endochondral ossification
Protein Families	Chondroitin N-acetylgalactosaminyltransferase family
Tissue Specificity	Ubiquitous, with the highest levels in placenta, thyroid, bladder, prostate and adrenal gland. Detected at low levels in the other tissues examined.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, IHC

Description

ELISA ; IHC, IHC ; ELISA

Dilution

IHC	1:50-1:100

Tested Application

ELISA,IHC;IHC:1:50-1:100

Datasheet
ELISA Protocol
Immunohistochemistry (IHC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558340	CSB-PA953607	100ul	$297		Add to Cart

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