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Home / Primary Antibodies / IHC Antibodies

CLDND1 Antibody

SKU : BHA10550324

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA271638
Alternative Names	claudin domain containing 1
Categories	Primary Antibodies
Description	CLDND1 (claudin domain containing 1), also known as C3orf4 or HSPC174, is a 253 amino acid multi-pass membrane protein that is expressed at high levels in adult brain and at lower levels in adult heart. Existing as two alternatively spliced isoforms, CLDND1 is encoded by a gene that maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
Host	Rabbit
Immunogen	Fusion protein of Human CLDND1
Isotype	IgG
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	CLDND1 (claudin domain containing 1), also known as C3orf4 or HSPC174, is a 253 amino acid multi-pass membrane protein that is expressed at high levels in adult brain and at lower levels in adult heart. Existing as two alternatively spliced isoforms, CLDND1 is encoded by a gene that maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
Species	Homo Sapiens (Human)
Subcellular Location	Membrane, Multi-pass membrane protein

Uniprot	Q9NY35
Database Links	HGNC:1322 KEGG:hsa:56650 STRING:9606.ENSP00000388457 UniGene:Hs.531371
Protein Families	PMP-22/EMP/MP20 family
Tissue Specificity	Widely distributed in the adult CNS with highest expression in the corpus callosum, caudate nucleus, cerebral cortex, medulla, putamen, spinal cord, substantia nigra and subthalamic nucleus. Weak expression was detected in the adult heart.

Buffer	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form	Liquid
Format	Liquid
Purification	Antigen affinity purification
Purity	Antigen affinity purification
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC, WB ; ELISA ; IHC

Dilution

ELISA	1:2000-1:5000
WB	1:200-1:1000
IHC	1:50-1:200

Tested Application

ELISA,WB,IHC;ELISA:1:2000-1:5000,WB:1:200-1:1000,IHC:1:50-1:200

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10550324	CSB-PA271638	100ul	$299		Add to Cart
BHA10550324	CSB-PA271638	50ul	$166		Add to Cart

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