Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons.van Slegtenhorst M.A., Hum. Mol. Genet. 3:547-552(1994).Kawasaki M., Am. J. Physiol. 277:C948-C954(1999).Rae J.L.; Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases.
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human CLCN4.
Involvement In Disease
Mental retardation, X-linked 49 (MRX49)
Raised In
Rabbit
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Relevance
Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons.
van Slegtenhorst M.A., Hum. Mol. Genet. 3:547-552(1994). Kawasaki M., Am. J. Physiol. 277:C948-C954(1999). Rae J.L.; Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases.
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total CLCN4 protein.
Subcellular Location
Early endosome membrane, Multi-pass membrane protein, Late endosome membrane, Multi-pass membrane protein, Endoplasmic reticulum membrane