Tumor necrosis factor receptor superfamily member 6B; Decoy receptor for Fas ligand; Decoy receptor 3; DcR3; M68
Antigen
CHST13
Categories
Primary Antibodies
Clonality
polyclonal
Description
Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Transfers sulfate to the C4 hydroxyl of beta1,4-linked GalNAc that is substituted with a beta-linked glucuronic acid at the C-3 hydroxyl. No activity toward dermatan.Kang H.-G., J. Biol. Chem. 277:34766-34772(2002).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human CHST13.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Transfers sulfate to the C4 hydroxyl of beta1,4-linked GalNAc that is substituted with a beta-linked glucuronic acid at the C-3 hydroxyl. No activity toward dermatan.
Kang H.-G., J. Biol. Chem. 277:34766-34772(2002).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total CHST13 protein.
Subcellular Location
Golgi apparatus membrane, Single-pass type II membrane protein
Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Transfers sulfate to the C4 hydroxyl of beta1,4-linked GalNAc that is substituted with a beta-linked glucuronic acid at the C-3 hydroxyl. No activity toward dermatan.
Protein Families
Sulfotransferase 2 family
Tissue Specificity
Highly expressed in adult liver. Expressed at lower level in kidney, lymph nodes and fetal kidney.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.