Ribosomal protein S6 kinase I; S6K; S6K1; 70 kDa ribosomal protein S6 kinase 1; p70 S6 kinase alpha
Antigen
CCNG1
Categories
Primary Antibodies
Clonality
polyclonal
Description
May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation By similarity.Philip J. Papst, et al. (1998) J. Biol. Chem; 273: 15077.Satoru Eguchi, et al. (999) J. Biol. Chem 1; 274: 36843.Ana Gonz篓顣抏z-Garc篓鐚
Host
Rabbit
Immunogen
Synthesized peptide derived from Human Cyclin G.
Raised In
Rabbit
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Relevance
May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation By similarity.
Philip J. Papst, et al. (1998) J. Biol. Chem; 273: 15077. Satoru Eguchi, et al. (999) J. Biol. Chem 1; 274: 36843. Ana Gonz?z-Garc
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total Cyclin G protein.
May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation (By similarity).
Pathway
p53 signaling pathway
Protein Families
Cyclin family, Cyclin G subfamily
Tissue Specificity
High levels in skeletal muscle, ovary, kidney and colon.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.