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Home / Primary Antibodies / IHC Antibodies

ARHGEF6 Antibody

SKU : BHA10555200

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA159616
Alternative Names	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
Categories	Primary Antibodies
Description	Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation.
Host	Rabbit
Immunogen	Synthetic peptide of human ARHGEF6
Involvement In Disease	Mental retardation, X-linked 46 (MRX46)
Isotype	IgG
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation.
Species	Homo Sapiens (Human)
Subcellular Location	Cell projection, lamellipodium

Uniprot	Q15052
Gene Id	9459
Database Links	HGNC:685 OMIM:300267 KEGG:hsa:9459 STRING:9606.ENSP00000250617 UniGene:Hs.522795
Function	Acts as a RAC1 guanine nucleotide exchange factor (GEF).
Pathway	Regulation of actin cytoskeleton
Tissue Specificity	Ubiquitous.
Weight	87,499 Da

Buffer	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form	Liquid
Format	Liquid
Purification	Antigen affinity purification
Purity	Antigen affinity purification
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Applications

ELISA, IHC

Description

ELISA ; IHC, IHC ; ELISA

Dilution

ELISA	1:1000-1:5000
IHC	1:50-1:200

Tested Application

ELISA,IHC;ELISA:1:1000-1:5000,IHC:1:50-1:200

Datasheet
ELISA Protocol
Immunohistochemistry (IHC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10555200	CSB-PA159616	100ul	$299		Add to Cart
BHA10555200	CSB-PA159616	50ul	$166		Add to Cart

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