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Home / Primary Antibodies / IHC Antibodies

AFF1 Antibody

SKU : BHA10557869

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA446654
Alternative Names	AF4; AFF1; FEL protein; MLLT2; Proto-oncogene AF4
Categories	Primary Antibodies
Clonality	polyclonal
Description	A chromosomal aberration involving AFF1 is associated with acute leukemias. Translocation t(4;11)(q21;q23) with MLL/HRX. The result is a rogue activator protein. Belongs to the AF4 family. Nakamura T., Proc. Natl. Acad. Sci. U.S.A. 90:4631-4635(1993).Morrissey J., Blood 81:1124-1131(1993).Gu Y., Cell 71:701-708(1992).
Host	Rabbit
Immunogen	Synthesized peptide derived from N-terminal of Human AF4.
Involvement In Disease	A chromosomal aberration involving AFF1 is associated with acute leukemias. Translocation t(4;11)(q21;q23) with KMT2A/MLL1. The result is a rogue activator protein.
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	A chromosomal aberration involving AFF1 is associated with acute leukemias. Translocation t(4;11)(q21;q23) with MLL/HRX. The result is a rogue activator protein. Belongs to the AF4 family.?Nakamura T., Proc. Natl. Acad. Sci. U.S.A. 90:4631-4635(1993).Morrissey J., Blood 81:1124-1131(1993).Gu Y., Cell 71:701-708(1992).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total AF4 protein.
Subcellular Location	Nucleus

Uniprot	P51825
Gene Id	4299
Database Links	HGNC:7135 OMIM:159557 KEGG:hsa:4299 STRING:9606.ENSP00000378578 UniGene:Hs.480190
Protein Families	AF4 family
Weight	131,578 Da

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, IHC

Description

ELISA ; IHC, IHC ; ELISA

Dilution

IHC	1:50-1:100

Tested Application

ELISA,IHC;IHC:1:50-1:100

Datasheet
ELISA Protocol
Immunohistochemistry (IHC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557869	CSB-PA446654	100ul	$297		Add to Cart

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