Anti-undefined Antibody MUC1,2278R Unconjugated BHA10208254

Mfr.No.	4582-RBM20-P1ABX
Alternative Names	Breast carcinoma-associated antigen DF3, CA15-3, Carcinoma-associated mucin Episialin, Epithelial Membrane Antigen, H23AG, KL-6, MAM6, MUC-1, MUC-1/SEC, MUC-1/X, MUC1-alpha, MUC1-beta, MUC1-CT, MUC1-NT, MUC1/ZD, Mucin 1 cell surface associated, Mucin-1 subunit beta, Peanut-reactive urinary mucin, PEM, PEMT, Polymorphic epithelial mucin, PUM, Tumor-associated epithelial membrane antigen
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic, Cell Surface
Chromosome Location	1q22
Clonality	monoclonal
Description	This MAb reacts with MUC1, a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia. It is used as tracer agent in CA15.3 assays. The extracellular domain of MUC1 largely consists of a highly conserved, O-glycosylated 20 amino acids tandem repeat which can occur 30-100 times per molecule depending on the length of the allele involved. In the vast majority of human carcinomas this protein is up-regulated and poorly glycosylated and appears on the cell surface in a non-polarized fashion. The dominant epitope of this MAb involves both amino acids as well as sugar moieties. Its epitope is destroyed by desialylation i.e. treatment with Neuraminidase.
Host	Rabbit
Immunogen	Human milk-fat globule membranes (HMFGM)
Isotype	IgG
Positive Control	MCF-7 or MDA-231 cells. Breast, colon, ovarian, endometrial carcinoma.
Reactivity	Human
Recombinant	TRUE
Regulatory	RUO

Swissprot	P15941
Gene Id	4582
Clone No	MUC1, 2278R
Symbol	MUC1
Weight	265-400kDa

Buffer	200μg/ml of recombinant MAb purified by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Storage	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Applications

IHC-F

Description

Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes,Optimal dilution for a specific application should be determined., IHC-F

Dilution

Immunohistology (Formalin-fixed)

0.5-1μg/ml for 30 minutes at RT

No Description Available.

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10208254	4582-RBM20-P1ABX	100µg	$393.20		Add to Cart

Anti-undefined Antibody MUC1,2278R Unconjugated BHA10208254

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