HPV-16 ; HPV-16 capsid ; HPV16 L1 ; HPV16 major capsid protein L1 ; Human papillomavirus type 16 L1 ; Human papillomavirus type 16 major capsid protein L1
Categories
Primary Antibodies
Cellular Localization
Nuclear
Clonality
monoclonal
Description
Reacts with a protein of 57kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). It is the major capsid protein of HPV-16. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33; very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.
Host
Mouse
Immunogen
Human papilloma virus type 16, major capsid protein L1
Isotype
IgG1
Positive Control
HPV-16 infected cells or cervical tissue
Reactivity
Type 16 of human Papilloma Virus (HPV-16)
Recombinant
TRUE
Regulatory
RUO
Clone No
rHPV16L1, 1058
Weight
57kDa
Buffer
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
1.0mg/ml
Description
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Storage
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Applications
IF, WBCLIP, IHC-FP
Description
Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes,Optimal dilution for a specific application should be determined., IF ; WBCLIP ; IHC-FP