Anti-undefined Antibody AIF1,2493 Unconjugated BHA10208062

Mfr.No.	199-MSM3-P1ABX
Alternative Names	Allograft inflammatory factor 1 (AIF1) ; balloon angioplasty responsive transcription (BART1) ; IBA1 ; Interferon responsive transcript 1 ; Ionized calcium-binding adapter molecule 1 ; IRT1 ; Microglia response factor (MRF1)
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic, Cell Surface
Chromosome Location	6p21.33
Clonality	monoclonal
Description	AIF1 is a cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. AIF1, containing two EF domains, is induced by cytokines and Interferons. In an unstimulated state, AIF1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding AIF1 resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC).
Host	Mouse
Immunogen	Purified recombinant human AIF1 protein (around aa 1-146) (exact sequence is proprietary)
Isotype	IgG2c Kappa
Positive Control	Lymph Node, Tonsil or Kidney
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P55008
Gene Id	199
Clone No	AIF1, 2493
Symbol	AIF1
Weight	17kDa

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Storage	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Applications

IHC-F

Description

Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes,Optimal dilution for a specific application should be determined., IHC-F

Dilution

Immunohistology (Formalin-fixed)

1-2μg/ml for 30 min at RT